Babe Original Lash Serum Contains a Prostaglandin: Who Should Skip It

Read the ingredient list before you look at the price. The Essential Lash Serum product page (October 2026) lists “Isopropyl Cloprostenate.” The brand also says the serum “contains a small amount of isopropyl cloprostenate, a synthetic prostaglandin analog.” That one line tells you more about whether the Babe Original lash serum suits you than any promise on the box.

Verdict: Skip It if You Are Pregnant, Nursing, Under 18 or Have Any Eye Condition

Essential suits adults with healthy eyes who accept a prostaglandin analogue. For everyone on its long skip list, it is a clear no.

The flaw: the label rules out a lot of people. The product page says not to use it in any of these cases:

• You are pregnant, nursing or under 18.
• You are undergoing therapy for glaucoma or cancer.
• You have ever had conjunctivitis, dry eyes, eye infections or styes.
• You have ever had irritation from other cosmetics applied in the eye area, or any eye-related disorder or illness.
• The skin is damaged or irritated.

The fix: if any line fits you, the label’s answer is no, so don’t buy it. Look at Babe’s prostaglandin-free Renewing Lash Serum and read its own warnings, or weigh the prescription option in the next step below with an eye doctor.

The strengths: the label names the prostaglandin analogue in plain words, the directions ease in over two weeks, and the stop rule is one line. The collection page also says Babe’s lash range is “Backed by our 90-Day Satisfaction Guarantee.”

Who should skip it: if you want no prostaglandin analogue at all, look at Babe’s Renewing Lash Serum. The collection page lists it as a prostaglandin-free peptide lash serum. Check its own ingredient list and price before you switch.

Babe Original Lash Serum Is a Prostaglandin Formula, Not Peptide-Only

Babe sells two kinds of lash serum. Its lash collection offers “Prostaglandin and peptide options for different sensitivities,” and Essential is the prostaglandin option. The product page calls isopropyl cloprostenate “a synthetic prostaglandin analog,” which means a lab-made version of a prostaglandin.

The marketing copy leads with biotin. The page says the serum is “powered by Biotin and Amino Acids to nourish lashes at the root,” while isopropyl cloprostenate sits near the end of the ingredient list.

Its headline promise is about looks: “visibly longer-looking lashes in as little as 4 weeks.” For what lash serum labels may claim, see why lash serum labels can only claim looks.

The Directions Start Slow: Every 2–3 Days, Then Nightly

The main direction is to apply the serum “once daily on a clean, dry upper lash line only,” per the product page. The full schedule on the same page eases in first and drops back later:

1. Start with a clean, dry upper lash line. The directions do not include the lower lashes.
2. Dip the brush once. One dip covers both eyes.
3. For the first two weeks, apply every 2–3 days.
4. After two weeks, apply nightly, never more than once a day.
5. Once you like how your lashes look, drop to 2–3 times a week.
6. Let the serum dry for 2–3 minutes before you put on other products.

Babe’s $49 Price Names No Size; Amazon Subscribe & Save Cuts It to $41.65

Babe lists a regular price of $49 on its product page (October 2026), but that price line does not name a size. The collection page sells Essential as a “Mini 6 Week Supply (1 mL),” a “3 Month Supply (2 mL)” and a “6 Month Supply (4 mL).”

That collection page shows a regular price of $29 beside the size list, without saying which size it buys. Check the mL in your cart before you work out a cost per mL.

On 27 October 2026, the main offer on the Amazon listing was sold by Babe Original and shipped from Amazon at $49.00. Three other new offers also started at $49.00. Bought once, Amazon matches the brand’s $49 to the cent.

Subscribe & Save cut the price to $41.65 (15% off), or to $39.20 at 20% off when 5 or more products ship in one delivery. That works out to $49.00 − $41.65 = $7.35 off each order. The listing says you can skip or cancel any time, so subscribe only if you plan to reorder.

To compare across brands, see GrandeLASH-MD cost per mL and who must skip it.

Shopper Check: The Skip List Matters More Than Where You Buy

What to check	What the source says	Who says it	What to do
Formula	Lists Isopropyl Cloprostenate, “a synthetic prostaglandin analog”	Brand, product page	Pick Renewing if you want no prostaglandin analogue
Who should skip	Pregnant, nursing or under 18; undergoing glaucoma or cancer therapy; ever had conjunctivitis, dry eyes, eye infections, styes, eye-area cosmetic irritation or any eye disorder; damaged or irritated skin	Brand, product page	Check yourself against the list before paying
Schedule	Every 2–3 days for two weeks, then nightly, then 2–3 times a week to keep the look	Brand, product page	Put the two-week switch in your calendar
Stop rule	Stop right away at redness, irritation or other unwanted effects	Brand, product page	Stop first, then ask an eye doctor
Price	Brand regular price $49, size not named; Amazon $49.00 sold by Babe Original, Subscribe & Save $41.65, on 27 Oct 2026	Brand and Amazon	Confirm the mL size, then compare prices
Hygiene	Misuse can let bacteria or fungi grow in eye cosmetics	FDA	Use it only as directed, and only on your own eyes

Stop at the First Sign of Redness

Babe’s stop rule is short: “If redness, irritation or other unwanted effects occur, stop using product immediately,” per the product page.

The FDA gives a general reason to use eye products carefully. It warns that misusing eye cosmetics “can allow dangerous bacteria or fungi to grow in them” (FDA eye cosmetic safety).

Babe’s page calls the serum “Clinically Tested” and “Ophthalmologist Tested,” and those tests are the brand’s own decision. The FDA explains why on its page about the Modernization of Cosmetics Regulation Act of 2022 (MoCRA). “Neither the law nor FDA regulations require specific tests to demonstrate the safety of individual products or ingredients,” it says (FDA MoCRA page). Either way, the skip list above is the part you can check against your own health.

Next Step: Compare It With the Prescription Option

Next step: if you are weighing a prescription lash product against cosmetic serums like this one, read Latisse vs OTC eyelash growth serum: which one is FDA approved.

Next step: read more in Lash serums on BetterLash, or check the figures in Lash serum ingredients and prices.

FAQ: Lower Lashes, Extensions and Cosmetic-or-Drug Status

Can I Put Babe Lash Serum on My Lower Lashes?

No. The brand’s directions say “upper lash line only.”

Can I Use It With Lash Extensions?

Babe’s product page talks about wearing your natural lashes “on their own, with mascara, or alongside falsies.” Whatever you wear, the direction stays the same: apply it only along the upper lash line.

Is Babe Essential a Cosmetic or a Drug?

Babe sells it as a cosmetic. Its product page says, “This cosmetic contains a small amount of Isopropyl Cloprostenate.” The FDA says the legal answer depends on a product’s intended use. A product “intended to affect the structure or any function of the body” counts as a drug.

Babe’s page promises “visibly longer-looking lashes” but also says the formula works “to nourish lashes at the root,” so the label alone does not settle the legal question.

This page describes cosmetic labels, prices and FDA guidance. It is not medical advice. If you have an eye condition, ask an eye doctor before using any lash serum.